Table 1 MicroRNA profiling of alpha-synuclein containing exosomes from H4 cell culture media
From: Exosomal cell-to-cell transmission of alpha synuclein oligomers
| miRNAs | function | remarks | Key citations |
|---|---|---|---|
| 7b | Inhibition of cell cycle progression and growth of melanoma cells | present in exosomes | [38, 39] |
| 7i | regulatory responses to microbial infection | present in exosomes | [40, 41] |
| 18b | exocytosis, angiogenesis, hematopoiesis, tumorgenesis | present in exosomes | [40] |
| 182 | Repression of tumor suppressors | present in exosomes | [39, 42] |
| 184 | Block of NFAT1 protein expression | present in exosomes | [40, 43] |
| 363* | - | [44, 45] | |
| 373* | Involvement in tumor migration and invasion | present in exosomes | [39, 46] |
| 375 | exocytosis, angiogenesis, hematopoiesis, tumorgenesis | present in exosomes | [39, 40] |
| 376* | - | [47, 48] | |
| 424 | controlling the macrophage differentiation program | present in exosomes | [39, 49] |
| 431 | - | CNS specific miRNA | [47, 50] |
| 455 | - | [51] | |
| 487a | Role in angiogenesis and cell aging | [52] | |
| 492 | - | [44] | |
| 494 | regulation of PTEN expression and functions as a micro-oncogene in carcinogenesis | present in exosomes | [39, 53] |
| 518c | - | [44, 54] |